777 Oil     Dolowhite Emulsion    A - Forte Capsules 
   Dano Anti Dandruff Hair Oil      Lippu Ointment     Bekay Capsules 
   Kesh Raksha Hair Oil     Psorolin Ointment    Caratol - E Capsules
   Lippu Oil     S.I.V.A drops       G - 7 Capsules
   Tolenorm Oil      Tolenorm Ointment      Pesin Capsules
   Eve fresh      Psorolin Medicated bathing bar      Lumina herbal shampoo
Prescribing information for the use by Hospital / Clinic / Laboratory
Pesin Capsules
 
 

Change the pace of treatment of Immune deficiencies and autoimmune disorders

Presenting

Pesin Capsules

A unique formulation that acts as an immuno-modulator

Pesin capsules help proliferation of the CD4 T-helper cells- Fights immune deficiency.

Human Immuno Deficiency Virus is an RNA virus that primarily affects the T-helper (CD4) cells. T-helper cells are the basic unit of immune surveillance and protection. A drug for HIV must address mainly two- areas viz. enhancing of the host’s immune system, especially the T-helper cells and destroy the virus by inhibiting the viral multiplication (reverse transcriptase inhibition).

 

A study to check the effect of PESIN on T-helper cell proliferation was done. The study involved oral feeding of PESIN and T-helper cell suppressive drug-Cyclosporin for a period 30 days with quantification of the T-helper and T-suppressor / cytotoxic cell ratio done at regular intervals. The control group was fed with only Cyclosporin.

The results showed significant effect of PESIN in ensuring T-helper cell proliferation and restoration to normal levels, in comparison to the control group where in the T-helper cell count declined sharply to nil during the period of investigation.

The therapeutic property of PESIN in enabling the immune system to be intact is a major step in the research and studies for an appropriate drug for HIV.

PESIN by virtue of its immuno modulator property has significant role in the treatment of autoimmune disorder like PSORIASIS. Prescription of PESIN during the severity stage of PSORIASIS for a period of 6 to 12 weeks greatly enhances the speed of remission. PESIN is hence co-prescribed with 777 oil and PSOROLIN ointment (Both products from Dr. JRK’s Siddha Research and Pharmaceuticals).

In addition, its ingredients have unique properties to overcome, painful joints, dyspepsia and depressions that commonly occur during severity stage and conditions of Psoriatic arthritis

Prescribing information

COMPOSITION:

Each 500 mg capsule contains
Extract of

 
Parangi pattai (Smilax chinensis) :100mg
Vaividangam (Embelia ribes ) :100mg
Amukkara (Withania somnifera) :125 mg
Elarisi (Elettaria cardamomum ) :100mg
Sangu parpam (Conch turbinella rapa parpam) :50 mg
Linga chenduram (Linga chendooram) 1 mg
Excipients Q.S
 

References

1. J.R.Krishnamoorthy et al ,Clinical experimental research study on certain herbal , mineral and metal compounds used in siddha medicine for management of venpadai vitiligo –Journal of research in Ayurveda and Siddha Vol XXII, NO 1-2(2001)

2. J.R.Krishnamoorthy et al , Immunomodulatory properties of certain siddha drug-PESIN and SIVA – Journal of research in ayurveda and siddha Vol XXIV, NO 1-2(2003)

3. J.R.Krishnamoorthy etal Therapeutic efficacy of PESIN and the role of metal moiety in increasing the bioavailabilty and efficacy of the drug –A pilot study –Journal of Indian medicine Vol –3 Oct/Dec-2003.

 

Indications

As supporting or supplementary therapy for immuno deficiency disorders and auto-immune disorders like Psoriasis, Chronic Dermatitis and Eczema. PESIN is specially indicated for the management of Psoriasis in severity stage when increased scaling is noted in the lesions. During such times, when multiple problems like painful joints, dyspepsia, general debility and depression are concurrently noted. PESIN is recommended as a supporting therapy along with 777 oil and Psorolin ointment for a period of 6 to 12 weeks.

Dosage / Administration
Adults: One capsule morning and two capsules at night after food with water or milk daily.
Children: Intake recommended for children above 10 years ,one capsule once a day after food with water or milk .
Diet and other recommendations

Intake of allergens like tomato, brinjals and certain types of fish that are likely to produce allergy, sour tasting food like tamarind should be minimized. A protein rich diet is recommended.

Presentation

Available in 50 nos. and 100 nos. capsule containers

 
    777 Oil     Dolowhite Emulsion    A - Forte Capsules 
   Dano Anti Dandruff Hair Oil      Lippu Ointment     Bekay Capsules 
   Kesh Raksha Hair Oil     Psorolin Ointment    Caratol - E Capsules
   Lippu Oil     S.I.V.A drops       G - 7 Capsules
   Tolenorm Oil      Tolenorm Ointment      Pesin Capsules
   Eve fresh      Psorolin Medicated bathing bar      Lumina herbal shampoo