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| Research findings of - Bekay CAPSULES |
Protective effect of Bekay against CCl4 induced hepatic damage in animals was studied.
The blood and serum parameters such as Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Alkaline phosphatase (ALP), Bilirubin, Total serum protein (TSP), Lipid peroxidation (LP), Superperoxidase dismutase (SOD), Catalase (CAT), Glutathione (GSH), Glycogen (GLY), Glutathione peroxidase (GPX) were determined in Bekay treated and non treated animals. The result is presented in the table 1.
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| Parameters |
Group 1 Normal animals (Mean) |
Group 2 CCl4 alone treated animals (Mean) |
Group 3 CCl4+ 10 mg BEKAY treated animals (Mean) |
Group 4 Cecium Chloride + 30 mg BEKAY treated animals (Mean) |
| ALT units/ml) |
64.12 |
129.02 |
89.2 |
68.89 |
| AST (units/ml) |
76.01 |
211.0 |
168.6 |
72.3 |
| ALP(KA units) |
60.0 |
113.0 |
93.1 |
71.0 |
| Bilirubin(mg%) Total |
0.110 |
2.89 |
1.65 |
1.01 |
| TSP(mg/ml) |
63.21 |
56.4 |
62.0 |
64.2 |
| LP(nmol of MDA formed/mg protein) |
129.6 |
197.3 |
145.6 |
118.0 |
| SOD(units of activcity/mg protein) |
1.06 |
0.79 |
0.98 |
1.0 |
| CAT(?moles of H2O2 decomposed/mg protein/minutes |
25.24 |
5.67 |
13.54 |
21.69 |
| GSH ?g/mg protein) |
6.23 |
1.36 |
3.66 |
6.01 |
| GLY(mg/g of wet tissue) |
29.23 |
19.22 |
21.2 |
27.8 |
| GPX (?g of glutathione consumed/min/mg protein) |
7.98 |
4.87 |
6.12 |
8.02 |
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