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Aloe Vera contains a new anti-inflammatory agent identified as C-Glucosyl Chromone viz. 8 - (C-beta-D (2-0-(E)-cinnamoyl) glucopyranosyl-2- -2- hydroxypropyl -7 methoxy - 5- methyl chromone. |
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C-Glucosyl Chromone exhibited topical anti-inflammatory activity equivalent to 200 micrograms/ear of hydrocortisone, with no reduction in thymus weight for any of the doses tested, while 200 micog/ ear of hydrocortisone, resulted in 50% reduction in thymus weight. |
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C-Glucosyl chromone showed significant anti-inflammatory activity in acute inflammatory model. An increase in Lysyl oxidase activity and mucopolysaccharide content were also seen. The drug with this ingredient therefore could increase tensile strength by increasing cross-linking in collagen and interactions with ground substance. |
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Active ingredients, Anthroquinone and Anthralic acid, isolated from Aloe Vera plant restrict the biosynthetic function of BRADYKININ, a substance causing pain and / or inflammation. Administered topically it helps alleviate inflammation. |
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Gugglu, Aloe Vera juice and oil of Sesamum indicum form an important ingredient of Vasavennai, a preparation in the traditional therapy / art VARMA KALAI. Varma therapy has preparations to bring back lost sensations in nerves and muscles. |