Kesh
Raksha Hair Oil is the Proprietary work of Dr.JRK's Siddha Research
& Pharmaceuticals (P) Limited.
Kesh Raksha Hair Oil and Kesh Raksha Hair Vitalizing cream,
the hair care preparations of the company promotes hair growth
by increasing the protein synthesis in the Dermal papila cells.
The total hair count assay in Guinea pig model revealed that
the oil and cream treatments significantly increases the hair
growth, time of growth and hair durability (analysis of amino
acid content of hair by HPLC).
Studies on the level of mRNA sysntesis (corresponds to protein
synthesis) in the matrix cells of the treated and untreated
hair was conducted.
An increased mRNA synthesis specific to Sonic Hedge Hog Gene(ShhcDNA)
was recorded.
We have used ShhcDNA as this gene was one the genes well studied
and reported to be responsible for hair growth in pre-natal
and post-natal stage.
Results of the study revealed that Kesh Raksha enhances the
anagen phase of the hair by increasing the protein synthesis
in the matrix cells.
Northern blot analysis of mRNA specific to Shh cDNA in treated
and control animals
(Text
Under)
Northern
blot analysis of mRNA specific to Shh cDNA in treated and control
animals
mRNA
expression patterns specific to Shh cDNA
in the hair follicle cells (matrix) collected
from oil treated and control area
Lane
1 and 2 are the mRNA
expression pattern of cream treated hair
Lane
3 Untreated (control)
Fig.1
mRNA
expression patterns specific to Shh cDNA
in the hair follicle cells (matrix) collected
from cream treated and control area
Lane
1a and 2a are the RNA expression
pattern of cream treated hair