Membrane bound adhesion of S.I.V.A drops molecules in the peritoneal phagocytes both during in vitro and in vivo tests was observed.

To reconfirm the boosting effect of SI.V.A on macrophage, we have conducted the challenge study, using candida as pathogen. the phagocyte mediated immunity was impaired with immuno suppressive drug and was challenged with candida cells .when S.I.V.A was administered ,the diseases per se was very insignificant when compared to S.I.V.A non treated control. This findings proves that S.I.V.A offers a very protective immuno boosting .

An effective immune surveillance and timely defence of the host system by the phagocytes (macrophages) are inventible for disease free life from a variety of pathogenic and opportunistic microbes that encompass us in the environment. S.I.V.A, the herbal formulation selectively boosts the phagocytic ability of the macrophages located at different regions of the body such as peritoneal cavity, alveolar space etc.,

S.I.V.A, a poly herbal proprietary oral preparation for boosting the macrophage (phagocytes) mediated immunity both by in vitro and in vivo carbon exclusion technique.     Specific effect of S.I.V.A treated phagocytes in killing of Candida cells was also established by uptake of tryphan blue staining method .

The present study clearly demonstrates that, S.I.V.A offer Sufficient immune protection especially in the disease per se . Of experimental candidiasis (Candida albicans ) . Tryphan blue staining (live cell staining) also revealed that death ratio of the fungal cells (Candida albicans and Aspergillus niger spores) ingested phagocytes in the test group (S.I.V.A treated phagocytes) was in the range of 20-30 % as against 60-70 % death in the case of control group .